Dr. Eran Stark, M.D.
Lab’s research
In our lab we study the way neuronal networks give rise to cognitive functions. We aim to understand the local circuit mechanisms which underlie various cognitive functions, focusing on the level of neuronal spiking.
In order to do so, we continuously develop new technologies which allow us to bi-directionally interface with the brain of free-behaving animals at the spatiotemporal resolution of a single neuron and of a single spike.
Our methodological approach combines high-density extracellular recordings with multi-site and multi-color electrical, optogenetic and pharmacological manipulations of dozens to hundreds of neurons simultaneously in freely moving rodents while performing behavioral tasks.
By recording, characterizing, and manipulating spiking activity of multiple neurons in real time, we "erase" and "write" individual spikes while observing the effect of these manipulations on behavior.
We believe our unique approach may help uncover the way the brain reads, writes, and codes information, thus shedding light on the neuronal mechanisms underlying cognition.